Custom Peptides
Cayman Chemical Metanephrine 10mg
An inactive metabolite of epinephrine; urinary and plasma levels are increased in patients with pheochromocytoma
Cayman Chemical ImIpenmhydrate 10mg
An intravenous β-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria (MICs range from 0.5-2 UG/ml for E. cloacae and P. aeruginosa), including several multi-drug resistant bacterial species
Cayman Chemical ElvItegravIr 10mg
A quinolone antibiotic that inhibits HIV-1 integrase (IC50 = 7.2 nM); has antiviral activity against laboratory strains and clinical isolates of HIV-1 in MAGI cells (EC50s = 0.1-1.26 nM) and HIV-2 in PBMCs (EC50s = 0.3-0.9)
Cayman Chemical JacarIc AcId 10mg
A conjugated PUFA that induces cell cycle arrest and apoptosis in a variety of cancer cell lines (GI50 = 1-5 µM); increases the production of ROS, leading to oxidative stress that contributes to cytotoxicity
Cayman Chemical MItoxntronhydrochlorIde 10mg
An inhibitor of DNA topoisomerase IIα and HIV-1 integrase (IC50s = 5.3 and 3.8 μM, respectively); intercalates DNA in a cell-free assay at 2 µM; inhibits DNA synthesis and induces DNA-protein crosslinks in vitro; inhibits the growth of K562 and K562-derived etoposide-resistant K/VP.5 cells (IC50s = 0.42 and 1.68 µM, respectively); inhibits HIV-1 integrase (IC50 = 3.8 μM); inhibits the membrane fusion of a mixed population of HEK293T cells expressing either ACE2 or the extracellular domain SARS-CoV-2 spike glycoprotein; inhibits the entry of SARS-CoV-2 into Vero E6 cells at 0.2 µM
Cayman Chemical GBR 12909hydrochlorIde 10mg
A potent inhibitor that blocks dopamine uptake (IC50 = 1-51 nM); effectively inhibits dopamine uptake in vivo, leading to consequent stimulation of dopamine receptors.
Cayman Chemical SotaglIflozIn 10mg
An SGLT inhibitor (IC50s = 36 and 1.8 nM for human SGLT1 and SGLT2, respectively); increases plasma GLP-1 and PYY levels, as well as glucose levels in the small intestine, cecum, and colon, in mice at 60 mg/kg; decreases blood glucose levels in a mouse model of cyclophosphamide-induced diabetes at 2 and 30 mg/kg
Cayman Chemical 7-methyl-6-ThIogunosIntec 10mg
A chromophoric substrate that is used to quantify inorganic phosphate (Pi) in the presence of purine nucleoside phosphorylase, followed by continuous spectrophotometry at an absorbance of 355-360 nm; used to measure changes in Pi levels in coupled enzyme systems
Cayman Chemical Rvaroxabn 10mg
An orally active, direct inhibitor of Factor Xa (Ki = 0.4 nM) that inhibits thrombin formation without prolonging bleeding time; approved for clinical use as an anticoagulant in the prevention of stroke and the treatment of venous thromboembolisms
Cayman Chemical aDGlucose1 6bIsphosphate 10mg
A bis-phosphorylated derivative of α-D-glucose; has roles in carbohydrate metabolism; the product of the reaction of glucose 1- or 6-phosphate with PGM2LI in the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate; a cofactor for the bacterial enzyme phosphopentomutase; has been used in the study of carbohydrate metabolism
Cayman Chemical DexmedetomIdInhydrochLRId 10mg
The (S)-enantiomer of medetomidine, an imidazole compound that binds to α2-adrenoceptors (Ki = 1.08 nM) with high affinity and selectivity; its activation of α2-adrenoceptors produces analgesic, sedative, and anxiolytic effects
Cayman Chemical TFMB-R-2-HG 10mg
A cell-permeable form of (R)-2-HG; has been used to assess the role of (R)-2-HG in leukemogenesis
Cayman Chemical mPIPhydrochlorIde 10mg
A reversible, selective, allosteric antagonist of mGluR7 that blocks agonist-induced calcium mobilization (IC50 = 26 nM)
Cayman Chemical 14-PentadecenoIc AcId 10mg
A 15-carbon, long-chain fatty acid that contains an alkene functional group on the terminal carbon of its aliphatic tail
Cayman Chemical MethsuxImIde 10mg
An anticonvulsant; inhibits CYP2C19-mediated metabolism of chlorproguanil and proguanil at 100 µM; protects against leptazol-induced convulsions in rats when administered at a dose of 100 mg/kg